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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFAP2A All Species: 33.03
Human Site: S428 Identified Species: 80.74
UniProt: P05549 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P05549 NP_001027451.1 437 48062 S428 H T D N N A K S S D K E E K H
Chimpanzee Pan troglodytes XP_001166719 439 48303 S430 H T D N N A K S S D K E E K H
Rhesus Macaque Macaca mulatta XP_001089006 689 75199 S680 H T D N N A K S S D K E E K H
Dog Lupus familis XP_848968 437 47999 S428 H T D N S A K S S D K E E K H
Cat Felis silvestris
Mouse Mus musculus P34056 437 47952 S428 H T D N S A K S S D K E E K H
Rat Rattus norvegicus P58197 437 47928 S428 H T D N S A K S S D K E E K H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514207 437 47981 S428 H T D N S A K S G D K E E K H
Chicken Gallus gallus NP_990425 437 47967 S428 H T D N S T K S S D K E E K H
Frog Xenopus laevis Q2T9K2 434 47032 S426 H S A A E S K S E K D I K H R
Zebra Danio Brachydanio rerio Q6P0E7 423 45495 H415 E N G G K N H H D K E L K H R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 58.4 99 N.A. 98.8 98.4 N.A. 97.9 93.5 67 59.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 61.5 99.5 N.A. 99.3 98.8 N.A. 98.8 96.3 79.4 75.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 86.6 86.6 20 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 40 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 70 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 80 0 0 0 0 0 10 80 10 0 0 0 0 % D
% Glu: 10 0 0 0 10 0 0 0 10 0 10 80 80 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 90 0 0 0 0 0 10 10 0 0 0 0 0 20 80 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 10 0 90 0 0 20 80 0 20 80 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 80 30 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % R
% Ser: 0 10 0 0 50 10 0 90 70 0 0 0 0 0 0 % S
% Thr: 0 80 0 0 0 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _